How to Become a Pharmacy Technician in Missouri

Checked against Missouri Board of Pharmacy (Division of Professional Registration) · Verified 2026-10-10

Exam: Not required
Training: Not required
Term: 1 years
State fee: $40 initial registration fee (20 CSR 2220-4.010)
Regulated by: Missouri Board of Pharmacy (Division of Professional Registration)

Take the free PTCB practice test →

Who can apply

Submit a pharmacy technician application with a 2x2 photo.
Complete a fingerprint-based criminal background check through the Board-approved vendor (MACHS).
National certification is not required to register.

Step by step

Apply online through the MOPRO licensing portal, upload a 2x2 photo, and pay the $40 fee. Paper applications are no longer accepted.
Schedule fingerprinting through the Missouri Automated Criminal History System (MACHS), use Registration Number 0003, and pay the vendor.
You may start working once your completed application (with photo and fee) and a fingerprint payment receipt are submitted. Keep copies of both at the pharmacy.
When approved, post your registration at the pharmacy or keep it in a central location your pharmacist-in-charge approves.
Renew every year before May 31.

Official application →

Training and exam

Exam: Not required to register. NCCA-accredited certification (PTCB or NHA/ExCPT) is required only to administer medications or vaccines, assist at a Class R remote dispensing site without a pharmacist present, assist at a Class Q charitable pharmacy, or do technology-assisted product verification.

No national exam required here. If you plan to get PTCB certified anyway, practice for the PTCE free →

What it costs in Missouri

Fixed amounts are set by the state. Items marked “your quote” are priced by private sellers, so enter what you’re quoted.

Initial registration fee$40
MACHS state and FBI fingerprint background check ($20 state + $13.25 FBI + $11.50 IDEMIA/IdentoGO service fee, paid to the vendor)$44.75

Estimated total in Missouri$84.75

Cost details from the state

Fingerprinting fee $44.75 paid to the MACHS vendor (subject to change)
Annual renewal fee $40

Pay in Missouri

Before you compare job offers, see what a paycheck takes home in Missouri after taxes.

Starting out on an entry-level wage? Check the SNAP income limits in Missouri by household size.

What other sites get wrong about Missouri

Myth: The Missouri pharmacy technician application fee is $35.

Fact: The Missouri Board of Pharmacy's initial technician registration fee is $40 (20 CSR 2220-4.010), and the annual renewal is also $40. source

Once you're registered

Renewal: Registrations are valid one year and expire every May 31; the renewal fee is $40. No continuing education is required to renew.

Good to know in Missouri

Start work while pending: You can begin working once you have been fingerprinted and paid, and have submitted a completed application with photo and fee. Keep the application copy and fingerprint receipt at the pharmacy.

Online only: Technician applications must now go through the MOPRO online portal; paper applications are returned.

90-day fingerprint window: Your fingerprint receipt must be dated no more than 90 days before you submit your application, or you must be re-fingerprinted and pay again. The MACHS registration confirmation page is not a receipt; you need the vendor's proof of payment.

Sources

General information, not legal advice. Fees and rules change — confirm with Missouri Board of Pharmacy (Division of Professional Registration) before you apply.